laiv bola - Types of seasonal influenza vaccine - World Health Organization (WHO) yupitoto

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Types of seasonal influenza vaccine - World Health Organization (WHO)

Abstract. The USA has a long-standing paediatric influenza vaccination programme, including use of live attenuated influenza vaccine (LAIV). Following US evidence of apparent lack of vaccine effectiveness (VE) of LAIV in 2015/2016, particularly against A (H1N1)pdm09, the USA suspended the use of LAIV in the 2016/2017 season.

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In Year 2, VE was 51.9% (95% CI 42.0 to 60.1) for LAIV and 49.9% (95% CI 39.2 to 58.7) for IIV; relative efficacy of LAIV compared with IIV was 4.2% (95% CI −19.9 to 23.5). We found that LAIV and IIV were safe and moderately efficacious against laboratory-confirmed influenza virus infection.

The recent wave of epidemic may also affect the vaccination plans for members of the public and thus a limited quantity of LAIV remains available. Compared to quadrivalent inactivated influenza vaccines, LAIV has more restrictions in administration of vaccines with a shorter shelf-life.